2010-2013


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Total Synthesis of Biotinylated N domain of Human Hepatocyte Growth Factor
Raibaut, L., Vicogne, J., Leclercq, B., Drobecq, H., Desmet, R., Melnyk, O. Bioorg. Med. Chem. 2013, 21 (12), 3486-94.

DOI : 10.1016/j.bmc.2013.02.043

 


Exploration of an imide capture/N,N-acyl shift sequence for asparagine native peptide bond formation
Mhidia, R., Boll, E., FĂ©court, F., Ermolenko, M., Ollivier, N., Sasaki, K., Crich, D., Delpech, B., Melnyk, O. Bioorg. Med. Chem. 2013, 21 (12), 3479-85.

DOI : 10.1016/j.bmc.2013.02.053

 


alpha-oxo aldehyde or glyoxylyl group chemistry in peptide bioconjugation
El-Mahdi, O. and Melnyk, O. Bioconjugate Chem. 2013, 24 (5), 735-65.

DOI : 10.1021/bc300516f

 


Highly efficient solid phase synthesis of large polypeptides by iterative ligations of bis(2-sulfanylethyl)amido (SEA) peptide segments
Raibaut, L., Adihou, H., Desmet, R., Delmas, A.F., Aucagne, V., Melnyk, O.
Chem. Sci. 2013, (4), 4061-4066.

DOI: 10.1039/C3SC51824H

 


Se-(9-Fluorenylmethyl) Selenoesters; Preparation, Reactivity and Use as Convenient Synthons for Selenoacids
Fecourt, F.; Delpech, B.; Melnyk, O.; Crich, D. Org. Lett. 2013, 15 (14), 3758-3761.

DOI: 10.1021/ol401677a

 


Synthesis of peptide thioacids at neutral pH using bis(2-sulfanylethyl)amido peptide precursors
Pira, S. L.; Boll, E.; Melnyk, O. Org. Lett. 2013, 15, 5346–5349.

DOI : 10.1021/ol402601j

 


Bis(2-sulfanylethyl)amido peptides enable Native Chemical Ligation at proline and minimize deletion side-product formation
Raibaut, L., Seeberger, P., and Melnyk, O. 2013, Org. Lett. 15, 5516–5519.

DOI: 10.1021/ol402678a

 

A Novel One-Pot Three Segments Ligation Strategy for Protein Chemical Synthesis
Ollivier, O., Vicogne, J., Vallin, A., Drobecq, H., Desmet, R., El Mahdi, O., Leclercq, B., Goormachtigh, G., Fafeur, F., Melnyk, O. Angewandte Chemie Int. Ed. 2012, 51, 209-13.

DOI : 10.1002/anie.201105837

 

Carbohydrate microarrays in 96-well polystyrene microtiter plates
Ebran, J. P., Dendane, N., and Melnyk, O. Methods Mol. Biol. 2012, 808, 377-91.

DOI : 10.1007/978-1-61779-373-8_25

 

Polysaccharide microarrays: application to the identification of heparan sulphate mimetics
Dheur, J., Dendane, N., Desmet, R., Dahmani, F., Goormachtigh, G., Vicogne, J., Fafeur, V., and Melnyk, O. Methods Mol. Biol. 2012, 808, 231-40.

DOI : 10.1007/978-1-61779-373-8_1

 

Access to cyclic or branched peptides using bis(2-sulfanylethyl)amido side-chain derivatives of Asp and Glu
Boll, E., Dheur, J., Drobecq, H., Melnyk, O. Org. Lett. 2012, 14, 2222-5.

DOI : 10.1021/ol30052Br

 

Sequential native peptide ligation strategies for total chemical protein synthesis
Raibaut, L., Ollivier, N., Melnyk, O. Chem. Soc. Rev. 2012, 41 (21), 7001-7015.

DOI : 10.1039/C2CS35147A

 

Direct characterization of native chemical ligation of peptides on hydrogenated silicon nanowires
Dendane, N., Melnyk, O., Xu, T., Grandidier, B., Boukherroub, R., Stievenard, D., Coffinier, Y. Langmuir 2012, 28, 13336-44.

DOI : 10.1021/la3030217

 

Shedding-generated Met receptor fragments can be routed to either the proteosomal or the lysosomal degradation pathway
Ancot, F., Leroy, C., Muharram, G., Lefebvre, J., Vicogne, J., Lemiere, A., Kherrouche, Z., Foveau, B., Pourtier, A., Melnyk, O., Giordano, S., ChotteauèLelievre, A., Tulasne, D. Traffic 2012, 13, 1261-72

DOI : 10.1111/j.1600-0854.2012.01384.x

 

Synthesis of thiazolidine thioester peptides and acceleration of native chemical ligation
Dheur, J., Ollivier, N., Melnyk, O. Org. Lett. 2011, 13, 1560-3.

DOI: 10.1021/ol2002804

 

Synthesis of peptide alkylthioesters using the intramolecular N,S-acyl shift properties of bis(2-sulfanylethyl)amido peptides
Dheur, J., Ollivier, N., Vallin, A., Oleg Melnyk J. Org. Chem. 2011, 76, 3194-202.

DOI : 10.1021/jo200029e

This article has been selected as a contribution to the American Chemical Society virtual collection "Peptides". To read the editorial of William Lubell see:
Editorial

To access to the contect of the Peptide ACS Virtual Collection:
Peptide ACS Virtual Collection

 

RYH: A minimal peptidic sequence obtained from beta-chain hemoglobin exhibiting an antimicrobial activity
Catiau, L., Traisnel, J., Chihib, N. E., Le Flem, G., Blanpain, A., Melnyk, O., Guillochon, D., and Nedjar-Arroume, N. Peptides 2011, 32, 1463-8.

DOI : 10.1016/j.peptides.2011.05.021

 

Three-Component Synthesis of Neoglycopeptides Using a Cu(II)-Triggered Aminolysis of Peptide Hydrazide Resin and an Azide-Alkyne Cycloaddition Sequence
Ebran, J. P., Dendane, N., and Melnyk, O. Org. Lett. 2011, 13, 4336-9.

DOI : 10.1021/ol201659x

 

In situ chemical modification of peptide microarrays: application to the study of the antibody responses to methylated antigens
Desmet R, Diesis E, Drobecq H, Rouanet C, Chemlal K, Debrie AS, Hougardy JM, Mascart F, Locht C, Melnyk O
Methods Mol Biol 2010 669:135-145.
doi:10.1007/978-1-60761-845-4_11

 

Photochemical immobilization of proteins and peptides on benzophenone-terminated boron-doped diamond surfaces
Marcon, Lionel; Wang, Mei; Coffinier, Yannick; Le Normand, Francois; Melnyk, Oleg; Boukherroub, Rabah; Szunerits, Sabine
Langmuir 2010, 26(2), 1075-1080.

DOI : 10.1021/la903012v

 

Selective cleavage of an azagly peptide bond by copper(II). Long-range effect of histidine residue
Reda Mhidia and Oleg Melnyk
Journal of Peptide Science 2010, 3, 141-7.

DOI: 10.1002/psc.1211

 

Synthesis of peptide-protein conjugates using N-succinimidyl carbamate chemistry
Reda Mhidia, Aurélie Vallin, Nathalie Ollivier, Annick Blanpain, Getao Shi, Romain Christiano, Ludger Johannes, Oleg Melnyk
Bioconjugate Chem. 2010, 21, 219-28.

DOI : 10.1021/bc900154r

 

Chemistry-based protein modification strategy for endocytic pathway analysis
Romain Christiano, Mohamed Amessou, Getao Shi, Michel Azoulay, Annick. Blanpain, Hervé Drobecq, Oleg Melnyk, Jean-Claude Florent, Ludger Johannes
Biology of the cell 2010, 6, 351-9.

DOI : 10.1042/BC20100008

 

NMR-based detection of acetylation sites in peptides
Smet-Nocca, C., Wieruszeski, J. M., Melnyk, O., and Benecke, A. . J Pept Sci 2010, 16, 414-23.

DOI : 10.1002/psc.1257

 

Assembly/disassembly of drug conjugates using imide ligation
Mhidia, R.; Bézière, N.; Blanpain, A.; Pommery, N.; Melnyk, O. Org. Lett. 2010, 12, 3982-5.

DOI : 10.1021/ol101049g

 

Bis(2-sulfanylethyl)amino Native Peptide Ligation
Ollivier, N., Dheur, J., Mhidia, R., Blanpain, A., Melnyk, O. Org Lett. 2010, 12, 5238-41.

DOI : 10.1021/ol102273u

 

Chips from Chips: Application to the Study of Antibody Responses to Methylated Proteins
Piret, G., Desmet, R., Diesis, E., Drobecq, H., Segers, J., Rouanet, C., Debrie, A. S., Boukherroub, R., Locht, C., and Melnyk, O. J. Proteome Res. 2010, 9, 6467-6478.

DOI : 10.1021/pr100707t