Highlights: Chem. Soc. Rev. 2019, Nat. Commun. 2018

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Total Chemical Synthesis of All SUMO-2/3 Dimer Combinations
Bouchenna, J. ; Sénéchal, M. ; Drobecq, H. ; Vicogne, J. ; Melnyk, O.
Bioconjugate Chem. 2019, 30, 11, 2967-2973.
DOI: 10.1021/acs.bioconjchem.9b00661

The Role of the Conserved SUMO-2/3 Cysteine Residue on Domain Structure Investigated Using Protein Chemical Synthesis
Bouchenna, J. ; Sénéchal, M. ; Drobecq, H. ; Stankovic-Valentin, N. ; Vicogne,* J. ; Melnyk, O. Bioconjugate Chem. 2019, 30, 2684-2696.
DOI : 10.1021/acs.bioconjchem.9b00598

Native chemical ligation and extended methodologies. Mechanisms, catalysis, scope and limitations
Agouridas, V. ; El Mahdi, O. ; Cargoët, M., Monbaliu, J.-C.- M ; Melnyk, O. Chem. Rev. 2019, 12, 7328-7443.
DOI : 10.1021/acs.chemrev.8b00712

Fast and facile preparation of nanostructured silicon surfaces for laser desorption/ionization mass spectrometry of small compounds
Hamdi, A.; Enjalbal, C.; Drobecq, H.; Boukherroub, R.; Melnyk, O.; Ezzaouia, H.; Coffinier, Y.,. Rapid Commun. Mass Spectrum 2019, 33, 66‐74.
DOI: 10.1002/rcm.8245

Accelerated microfluidic native chemical ligation at difficult amino acids toward cyclic peptides
Ollivier, O ; Toupy, T. ; Hartkoorn, R. C. ; Desmet, R. ; Monbaliu, J.-C. M ; Melnyk, O.
Nat Commun. 2018, p. 2847. DOI: 10.1038/s41467-018-05264-8

This article has ben highlighted in Synfacts (Synfact of the month)
Native Chemical Ligation by Microflow Chemistry
Contributor(s): Hisashi Yamamoto, Takahiro Sawano
Synfacts 2019; 15(02): 0203
DOI: 10.1055/s-0037-1611960

Catalysis of thiol-thioester exchange by water-soluble alkyldiselenols applied to the synthesis of peptide thioesters and SEA-mediated ligation
Cargoet, M.; Diemer, V.; Snella, B.; Desmet, R.; Blanpain, A.; Drobecq, H.; Agouridas, V.; Melnyk, O. J. Org. Chem. 2018, 83, pp 12584–12594.
DOI: 10.1021/acs.joc.8b01903

Hypoxia leads to decreased autophosphorylation of the MET receptor but promotes its resistance to tyrosine kinase inhibitors
Mekki, M. S.; Mougel, A.; Vinchent, A.; Paquet, C.; Copin, M. C.; Leroy, C.; Kherrouche, Z.; Bonte, J. P.; Melnyk, O.; Vicogne, J.; Tulasne, D.,. Oncotarget 2018, 9 (43), 27039-27058.
DOI: 10.18632/oncotarget.25472

Native chemical ligation at serine revisited
Snella, B.; Diemer, V.; Drobecq, H.; Agouridas, V.; Melnyk, O. Org. Lett. 2018, 20, 7616–7619.
DOI : 10.1021/acs.orglett.8b03355