Main research interests

There is space for plenty of discoveries

Large proteins cannot be usually synthesized using conventional stepwise solid phase methods. Therefore, there is a need for chemical methods allowing the convergent synthesis of large polypeptides by linking together short peptide fragments in a controlled manner. The great challenge is the necessity to form a native peptide bond using unprotected peptide fragments and in aqueous solution (for solubilizing peptide fragments).
Our goal is to design and develop novel chemical method for chemoselective native peptide bond formation that can be complementary to existing methods.


->Inventing methods for protein chemical synthesis